Estradiol

Estradiol is the most potent and abundant form of estrogen, a female sex hormone. While primarily associated with the female reproductive system, it plays a vital role in both women and men, affecting numerous bodily functions. 

Estradiol is an estrogen steroid hormone derived from the cholesterol molecule. During the reproductive period, the granulosa cells in the ovaries produce estradiol from androstenedione. Minor quantities are produced in the adrenal gland, fat cells, the brain, arterial walls and placenta. In men, the testes produce a small amount of estradiol, which is important in erectile function, sperm maturation and modulating libido